The prevalence of low-density-lipoprotein-receptor-associated protein 4 (LRP4) autoantibodies is higher in children and females with myasthenia gravis, with clinical manifestations often involving ocular and limb muscles.
Why this matters
LRP4 antibodies have recently been identified in people with myasthenia gravis (MG), however, the clinical features have not been previously described.
Further understanding of the different serological sub-types will help to predict disease severity and prognosis and will guide treatment strategies in people with MG.
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