Imaging of tau fibrils implies distinct and synergistic contributions of gray and white matter tau pathologies to symptoms of progressive supranuclear palsy

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Abstract

BACKGROUND:

[11 C]pyridinyl-butadienyl-benzothiazole 3 is a PET imaging agent designed for capturing pathological tau aggregates in diverse neurodegenerative disorders, and would be of clinical utility for neuropathological investigations of PSP. 

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© 2019 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.